BOC-(S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-ACETIC ACID

BOC-(S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-ACETIC ACID - Names and Identifiers

Name	Boc-(S)-2-tetrahydroisoquinoline acetic acid
Synonyms	BOC-TQA-OH BOC-TIC-(C*CH2)OH BOC-L-Β-HMOC-TIC-OH Boc-(S)-2-tetrahydroisoquinoline acetic acid BOC-(S)-2-TETRAHYDROISOQUINOLINE ACETIC ACID BOC-(S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-ACETIC ACID (S)-2-(2-Boc-1,2,3,4-tetrahydro-3-isoquinolyl)acetic Acid N-T-BUTOXYCARBONYL-(S)-2-TETRAHYDROISOQUINOLINE ACETIC ACID N-(tert-Butoxycarbonyl)-(S)-1,2,3,4-tetrahydroisoquinoline-3-acetic acid
CAS	270062-98-1

BOC-(S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-ACETIC ACID - Physico-chemical Properties

Molecular Formula	C16H21NO4
Molar Mass	291.34
Density	1.180
Boling Point	454.5±38.0 °C(Predicted)
pKa	4.44±0.10(Predicted)
Storage Condition	2-8°C

BOC-(S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-ACETIC ACID - Risk and Safety

Risk Codes	R25 - Toxic if swallowed R50 - Very Toxic to aquatic organisms
Safety Description	S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
Hazard Class	IRRITANT

BOC-(S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-ACETIC ACID - Introduction

Boc-(S)-2-tetrahydroisoquinoline acetic acid is an organic compound with the chemical formula C13H19NO3. The following is a description of its nature, use, preparation and safety information:

Nature:
Boc-(S)-2-tetrahydroisoquinoline acid is a white solid powder. It has low solubility and can be dissolved in solvents such as ethanol, methanol and chloroform. It has a melting point of about 85-90°C.

Use:
Boc-(S)-2-tetrahydroisoquinoline acetic acid is an organic synthetic compound, commonly used in the synthesis of chiral compounds and the preparation of intermediates. It can be used as a precursor of chiral catalyst or ligand, which is very important for asymmetric synthesis and preparation of chiral drugs.

Preparation Method:
The synthesis of Boc-(S)-2-tetrahydroisoquinoline acetic acid is usually carried out by the following steps:
1. The Boc protecting group is introduced into the isoquinoline skeleton. This can be achieved by reacting the Boc-sulfoxoamine with isoquinoline.
2. The introduction of acetic acid group into tetrahydroisoquinoline can usually be completed by adding acetic anhydride and catalyst in the reaction.

Safety Information:
Boc-(S)-2-tetrahydroisoquinoline acetic acid is a chemical and should be handled in accordance with safe operating procedures. It may be irritating to the eyes and skin, so you should wear appropriate protective measures such as glasses and laboratory gloves. In addition, it should be operated in a well-ventilated area to avoid inhalation of dust or contact with its solution. In case of accidental splashing into eyes or skin, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 20:52:54